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In our various clinical programs at Â鶹¹û¶³´«Ã½ Children’s Health, we treat a variety of end-stage lung and pulmonary vascular diseases with transplantation. Specific conditions that may require transplantation include:   

Pulmonary vascular disease

• Pulmonary hypertension (PH)
• Pulmonary veno-occlusive disease (PVOD)
• Alveolar capillary dysplasia (ACD)
• Bilateral pulmonary vein stenosis (PVS) with or without congenital heart disease

Learn more about pulmonary vascular disease >

Chronic lung disease with secondary pulmonary hypertension

Learn more about advanced lung disease >

Primary pulmonary disease

• Cystic fibrosis (CF)
• Heritable surfactant deficiencies, including but not limited to:
  • Surfactant protein B
  • Surfactant protein C
  • NKX2.1 disease (brain-thyroid-lung syndrome)
  • ABCA3 deficiency
• Obliterative bronchiolitis or bronchiolitis obliterans
• Chronic lung graft versus host disease (GVHD) after stem cell transplant
• Pulmonary fibrosis
• Bronchiectasis (not CF-related)
• Chronic lung failure after acute respiratory distress syndrome

Pulmonary disease with a vascular component

• FLNA (Filamin A gene) disease
• TBX4 disease

Congenital heart disease

• Congenital heart disease with pulmonary hypertension
• Congenital heart disease with pulmonary vein or pulmonary artery stenosis
• Eisenmenger syndrome