麻豆果冻传媒

For Release: October 21, 2014

STANFORD, Calif. 鈥� On October 17, 2013, Jennifer and Ken Zimmerman got the life-altering prognosis that their 7-year-old daughter, Emily, had a tumor the size of a golf ball in her brain and doctors suspected it was an aggressive cancer.

鈥淎t the time, we didn鈥檛 know if it was a death sentence,鈥� said Ken Zimmerman.

What they did know is that the doctors weren鈥檛 wasting any time. Only moments after receiving the diagnosis, Jennifer Zimmerman was instructed to bring Emily directly to their local Reno emergency room so she could be transported by Life Flight to Lucile Packard Children鈥檚 Hospital Stanford 250 miles away.

鈥淚 don鈥檛 even remember driving there,鈥� said Jennifer, who bundled her daughter into the car, drove to the nearest Life Flight pad and called her husband at work to tell him to meet them at Stanford 鈥� there wasn鈥檛 enough room on Life Flight for the three of them.

Emily鈥檚 symptoms had started in August following an Alaskan vacation. When they got home from the trip she complained of headaches. At the time, the Rim Fire in Northern California raged and Emily鈥檚 pediatrician initially thought smoke from the blaze could be causing the headaches, Jennifer said.

But even after the fire was out, Emily continued to have the headaches and would wake in the middle of the night with sweats. When Jennifer found her daughter vomiting one morning, she took Emily back to the doctor and insisted that they run tests, including an MRI. That鈥檚 when the doctors found the tumor.

By the time Jennifer and Emily arrived at Stanford that same day, Gerald Grant, MD, chief of pediatric neurosurgery at Stanford Children鈥檚 Health, and his team were waiting to discuss treatment.

鈥淎t this point we didn鈥檛 know if the tumor was operable,鈥� Jennifer said. 鈥淲e didn鈥檛 know if they would try to shrink it with chemotherapy or radiation. We didn鈥檛 know what was going to happen to our daughter.鈥�

Grant, also an associate professor of neurosurgery at the , didn鈥檛 give them time to wonder.

鈥淭hat thing is coming out on Saturday,鈥� Jennifer remembered Grant telling her. 鈥淚 can鈥檛 explain the wave of emotion that came over me. Here it was Thursday and they planned to take the tumor out in two days. I felt so much relief when he said this and had total confidence in Dr. Grant and his team.鈥�

Yet, the parents knew that the operation had risks

鈥淭his kind of surgery is one of the most difficult surgeries we do as pediatric neurosurgeons,鈥� said Grant, adding that typically the operation takes six to eight hours and if the tumor is malignant, and if the cancer has infiltrated into critical areas of the brain, the risks of removal grows. 鈥淲e can be very aggressive with surgery, although there is always a cost which may negatively impact Emily鈥檚 quality of life.鈥�

The risks include losing cognitive skills, such as speech called mutism, problems with coordination, or movement and double vision. 鈥淭hese types of surgeries are routinely performed by our team at Stanford since we specialize in pediatric brain tumors,鈥� Grant said, citing an 85-90 percent success rate. 鈥淲e are limited by the unfortunate spread of the cancer into areas of the brain which we cannot safely enter without causing permanent harm. We therefore need to love the child more than we hate the cancer to perform the safest operation possible.鈥�

Grant and his neurosurgery team successfully removed Emily鈥檚 tumor and ultimately concluded that she had medulloblastoma, a fast-growing cancer, located in the cerebellum, the lower, rear area of the brain. It is most commonly diagnosed in children younger than 10, although doctors don鈥檛 know the cause. Grant said the Zimmermans got to Lucile Packard Children鈥檚 Hospital just in the nick of time. Although the cancer hadn鈥檛 yet spread, doctors feared other complications, like water on the brain.

鈥淓mily鈥檚 symptoms were signs of increased water on the brain due to the blockage of the normal spinal fluid drainage pathways in the brain. Emily was so fortunate that she had the MRI scan before she got even sicker. Some children arrive in a coma from the hydrocephalus alone and the prognosis for recovery can be very guarded,鈥� Grant said, adding that Emily was nearing that point, but that the use of high- dose steroids helped counteract the symptoms of the hydrocephalus until she went to surgery.

Since the surgery and numerous chemotherapy and radiation treatments that followed, Emily remains cancer-free. Jennifer said it was not all easy going. For a short time after the operation, Emily lost her speech and had to learn how to walk again. But the third-grader has put that behind her now, going back to her pre-cancer world, when family vacations, Barbies and social clubs like Brownies consumed her life. 鈥淪he鈥檒l need to have MRIs for the rest of her life,鈥� Jennifer acknowledged.

Because Lucile Packard Children鈥檚 Hospital Stanford conducts cutting-edge brain tumor research in association with the School of Medicine, it will continue studying Emily鈥檚 specific case. On the day of surgery, Emily鈥檚 tumor was frozen down and cultured in a dish so we could implant the tumor in mice to better understand how these tumors grow, why they form, and continue to find novel treatments to cure these malignant tumors.

鈥淚鈥檓 so eternally grateful to Dr. Grant and his team,鈥� Jennifer Zimmerman said. 鈥淭o have this level of care for our daughter is our greatest relief.鈥�

Authors

Media contact:
Robert Dicks
麻豆果冻传媒 Children's Health
Lucile Packard Children's Hospital
(650) 497-8364
rdicks@stanfordchildrens.org